A SART DATA COST-EFFECTIVENESS ANALYSIS OF PLANNED OOCYTE CRYOPRESERVATION VERSUS IN VITRO FERTILIZATION WITH PREIMPLANTATION GENETIC TESTING FOR ANEUPLOIDY CONSIDERING IDEAL FAMILY SIZE
Using the SART-CORS database, this study evaluated the cost-effectiveness of oocyte cryopreservation as a mean of deferred reproductive as opposed to no oocyte cryopreservation with IVF and PGT-A testing at advanced reproductive age in women desiring one or two live births. Notable findings from the study include for women desiring one child, a higher chance of live birth occurs if oocyte cryopreservation occurs before age 39, with the highest chance of live birth occurring when oocyte cryopreservation occurs before age 32. Women desiring two children saw the most success when one cycle of oocyte cryopreservation occurred before age 37 and two cycles before age 39 rather than IVF with PGT-A at an advanced age. In this group, women had highest success of live birth when two cycles of oocyte cryopreservation occurred before age 31. Analysis of the data suggests that oocyte cryopreservation is a cost-effective strategy for delayed childbearing. This study is important as more patients are choosing to delay childbearing and incorporate ART into their family building.