ANTIOXIDANT INTERVENTION AGAINST MALE INFERTILITY: TIME TO DESIGN NOVEL STRATEGIES
Ávila C, Vinay JI, Arese M, Saso L, Rodrigo R. “Antioxidant Intervention against Male Infertility: Time to Design Novel Strategies”. Biomedicines. 2022 Nov. doi: 10.3390/biomedicines10123058.
Recent findings in research have indicated that reactive oxygen species pathophysiology influences male infertility, but an antioxidant therapy to treat male infertility has yet to be introduced. This review provides an in-depth analysis of the literature regarding antioxidants and oxidative stress as contributors to male infertility and identifies gaps in the current literature. Authors identify a need for therapeutics and interventions that are based on the time course of spermatogenesis and oxidative stress, as well as provide a summary of sources of reactive oxygen species that may contribute to male infertility.