PREGNANCY OUTCOMES AFTER ORAL AND INJECTABLE OVULATION INDUCTION IN WOMEN WITH INFERTILITY WITH A LOW ANTIMÜLLERIAN HORMONE LEVEL COMPARED WITH THOSE WITH A NORMAL ANTIMÜLLERIAN HORMONE LEVEL
This retrospective cohort study was initiated to determine the ongoing pregnancy rate among women diagnosed with infertility with low level of antimullerian hormone level compared to those with normal antimullerian hormone levels after oral and injectable ovulation induction/intrauterine insemination (OI/IUI). A total of 7,169 OI/IUI cycles were included: 3,122 patients completed 5,539 oral antiestrogen cycles and 1,060 women completed 1,630 injectable gonadotropin cycles at a large academic center between 2015 and 2019. Significant findings from the study include: women over the age of 35 and 35-40 years old with low AMH treated with injectable gonadotropins had a significantly reduced ongoing pregnancy rate compared to women of similar age with normal AMH levels. The difference is likely due to an unexpectedly high ongoing pregnancy rate in the normal AMH group. The decline in ongoing pregnancy rate corresponds with a reduction in AMH from 1.0 ng/mL in this cohort of women.